Adjusting acidity with impunity

How do individual cells or proteins react to changing pH levels? Researchers at the MESA+ Institute for Nanotechnology at the University of Twente have developed a technique for ‘gently’ adjusting pH: in other words, without damaging biomolecules. This should soon allow them to measure the activity of a single enzyme as a function of pH. The researchers will publish their findings in the journal Lab on a Chip, which will devote a cover story to their research in the December 21st issue.

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